The Faculty of Medicine, Medisetter Co., Ltd and ThermoFisher Scientific to organized a scientific conference on using antibiotics in the 21st century

(VLU - 18/6/2021) - At 14:00 on June 17, 2021, the Faculty of Medicine - Van Lang University, Medisetter Vietnam, and Thermo Fisher Scientific co-organized the webinar " Antibiotics Stewardship Program in the 21st Century: Challenges and Solutions ".

The keynote speakers for this webinar was by Dr. Pham Hung Van, Philosophy Doctor of Epidemiology and Microbiology, Chairman of the Vietnam Association of Clinical Microbiology HCMC; Mr. Tran Nhat Phuong, Philosophy Doctor of Microbiology, Head of Basic Medical Sciences Department, Medicine Faculty, Van Lang University; M.B.B.S., MD. Neha Mishra, Consultant, Department of Infectious Diseases, Manipal Hospitals, Bangalore, India.

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Opening the webinar, Dr. Pham Hung Van, PhD alarmed the further increasing of  antibiotic resistance  over the past decade. The problem of antibiotic resistance has been reported more and more serverly in specialized journals of microbiology and infectious diseases. The situation is different from what it used to be, most doctors downplayed the phrase "antibiotic-resistant bacteria" because at that time the empirically prescribed antibiotics still seemed to work well on the most harmful bacteria.

According to Dr. Pham Hung Van, the situation of antibiotic resistance has become a global issue, especially in developing countries with infectious diseases still accounting for a high proportion in the disease structure such as gastrointestinal and respiratory tract infections., sexually transmitted diseases and nosocomial infections... The mandatory replacement of old antibiotics with expensive new ones is a real burden because of increasing costs for health care.

Why are bacteria resistant to antibiotics?

Over the past 100 years, thousands of antibiotics have been found and put into use. There are 3 basic types of antibiotics, which are natural, semi-synthetic and synthetic antibiotics. Thanks to antibiotics, in World War II, the soldiers' wounds could easily recover. At this time, humanity thought that they could solve the problem of bacteria due to the advent of antibiotics. However, what happened in reality showed the opposite. Bacteria are mutating and adapting to resist most of antibiotics. It's surprising that bacteria have so many ways to deal with antibiotics and we always fall behind to find out the new ones. Whenever new antibiotics have just been put into widespread use, soon after, bacteria developed resistant mechanisms to that antibiotic.

The most common cause leading to the above situation, as per Dr. Pham Hung Van, is overusing or inappropriate using of antibiotics, especially in hospitals. The bacteria that are resistant to antibiotics are collectively known as the ESKAPE group. This kind of bacteria have widely spread in community, hospital environments and is transmitted through daily food sources.Having cited the statement of Dr. KiDong Park (Chief Officer of WHO Representative in Vietnam):

“We are losing this essential tools to fight common pathogens. We are slowly running out of this precious resource. New drug development is needed. However, if people do not change the way they are using antibiotics, even the new drugs release, they will soon become ineffective”

Dr. Tran Nhat Phuong summarized the current situation of antibiotic resistance. With experience in research and teaching, Dr. Phuong added that the multi-drug resistant bacteria in the 21st century are mostly Gram-negative. In Vietnam, from 2015 to 2017, through 12,436 gram-negative bacteria isolated at Viet Tiep General Hospital (Hai Phong), the rate of antibiotic-resistant bacteria increased over time of use. At the same time, at Gia Dinh People's Hospital (HCMC) and Bach Mai Hospital (Hanoi) there were also cases of antibiotic resistance at the same rate.

In agreement with Dr. Pham Hung Van and Dr. Tran Nhat Phuong, Dr. Neha Mishra said that, not only in Vietnam, the burden of antibiotic resistance within pathogens due to overusing has also continuously increased in recent years in India. According to Dr.Neha Mishra, before using an antibiotic, we needs to have many different analysis, because even a small mistake can lead to the emergence of many different strains of antibiotic-resistant pathogens, making the treatment become much more difficult, even the simplest diseases

A lot of control measures to tackle antibiotic resistance were outlined by the three speakers. In addition to the fact that doctors need to give a reasonable antibiotic treatment plan before using antibiotics, the patients also play an important role. Using antibiotics without instructions or prescriptions from doctors also leads to antibiotic resistance of bacteria.

Watch the full webinar here.

Huynh Bao

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